生理科学与临床

“咖啡与健康”系列——咖啡摄入与痤疮发病:潜在益处与风险分析

展开
  • (1 北京大学基础医学院,北京 100191; 2 北京大学基础医学院生物化学与分子生物学系, 北京 100191)
△ shuyanli@pku.edu.cn

收稿日期: 2025-07-23

  修回日期: 2025-08-21

  录用日期: 2025-08-23

  网络出版日期: 2025-10-25

基金资助

北大医学瑞幸健康创新基金RX-CX202501资助课题

Coffee Consumption and Acne Pathogenesis: Analysis of Potential Benefits and Risks

Expand
  • (1 School of Basic Medical Sciences, Peking University, Beijing 100191, China; 2 Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University, Beijing 100191, China)
△ shuyanli@pku.edu.cn

Received date: 2025-07-23

  Revised date: 2025-08-21

  Accepted date: 2025-08-23

  Online published: 2025-10-25

摘要

寻常痤疮(acne vulgaris)是常见慢性炎症性皮肤病,广泛影响青少年及部分成年人群。咖啡作为全球消费量巨大的饮品,其对皮肤健康,尤其是痤疮的影响,正日益受到关注。研究表明, 咖啡内含的咖啡因、绿原酸等成分具有抗氧化、抗炎和调节脂质代谢等作用,可能有益于抑制痤疮的发生。此外,咖啡可能通过肠-皮肤轴调节肠道菌群,间接影响皮肤健康。然而,咖啡的摄入效果受个体差异影响显著,同时咖啡中的糖和乳制品等添加成分可能加重炎症,抵消其潜在益处。本文综述了咖啡及其主要成分对寻常痤疮的影响及可能机制,为揭示咖啡摄入及其与皮肤健康的潜在联系提供理论依据和科学指导。

本文引用格式

罗丹妮1, 李淑艳2, △ . “咖啡与健康”系列——咖啡摄入与痤疮发病:潜在益处与风险分析[J]. 生理科学进展, 2025 , 56(5) : 468 -473 . DOI: 10.20059/j.cnki.pps.2025.09.1234

Abstract

Acne vulgaris is a common chronic inflammatory skin disease that affects a wide range of adolescents and some adults. As a globally consumed beverage, coffee's effects on skin health, particularly on acne vulgaris, have attracted increasing attention. Research suggests that coffee constituents, such as caffeine and chlorogenic acid, may exert beneficial effects on acne suppression through their antioxidant, anti-inflammatory, and lipid-regulatory properties. Additionally, coffee may indirectly influence skin health by modulating the gut microbiota through the gut-skin axis. However, the effects of coffee consumption are significantly influenced by individual variability, and additives such as sugar and dairy products in coffee may exacerbate inflammation, potentially counteracting its benefits. This review summarizes current evidence regarding the effects and potential mechanisms of coffee and its major components on acne vulgaris, aiming to provide a theoretical basis and scientific guidance for understanding the potential link between coffee consumption and skin health.
Options
文章导航

/