抗肿瘤药物(anti-tumor drugs)尤其是化疗药物因具有价格低廉、疗效显著等优势成为目前最为广泛的治疗癌症的方法,然而其在使用过程中的毒副作用尤其是心脏毒性(cardiotoxicity)作用极大限制了该类药物的临床应用。随着活性成分提取、纳米材料等新兴技术的不断发展, 越来越多的策略被开发用于减轻抗肿瘤药物导致的心脏毒性。本文从抗肿瘤药物引发心脏毒性的机制入手，目前缓解抗肿瘤药物心脏毒性的干预策略的研究进展进行综述,以期为更安全的癌症治疗提供新的思路与方向。

Anti-tumor drugs, especially chemotherapy drugs, are among the most widely employed approaches for cancer treatment due to their cost-effectiveness and significant therapeutic efficacy. However, their side effects, particularly cardiotoxicity, significantly limit their clinical application. With advancements in biotechnologies, such as active ingredient extraction and nanomaterials, an increasing number of strategies have been developed to mitigate the cardiotoxicity caused by anti-tumor drugs. This review elucidates the potential mechanisms underlying antitumor drug-induced cardiotoxicity, summarizes current research progress on cardioprotective interventions, and provides insights into potential strategies for achieving safer cancer treatment.