专论

COVID-19相关心肌炎的研究进展

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  • (中国医科大学药学院 药物毒理学教研室,沈阳110122)

收稿日期: 2023-06-21

  修回日期: 2023-08-05

  录用日期: 2023-08-08

  网络出版日期: 2024-04-25

基金资助

国家自然科学基金(81100108);辽宁省教育厅基本科研项目(JYTMS20230130);中国医科大学新冠肺炎疫情防控相关科研攻关项目(2020-07)资助课题

Research Progress on COVID-19-Related Myocarditis

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  • (Department of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China )

Received date: 2023-06-21

  Revised date: 2023-08-05

  Accepted date: 2023-08-08

  Online published: 2024-04-25

摘要

严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronavirus 2,SARSCoV-2)是一种新型冠状病毒,主要感染肺脏造成新型冠状病毒肺炎(coronavirus disease 2019, COVID-19)。近年的临床病例报告了其心血管系统并发症主要为心肌炎、心律失常、心肌梗死等。其中,COVID-19相关心肌炎症状多样,不同年龄段均可发生,存在延迟发作,且与COVID-19患者的不良预后和死亡率呈正相关。因此,研究其临床特点、潜在发病机制和治疗方法可对未来COVID-19相关心肌炎的防治及药物开发提供新的思路和策略。本文将结合国内外关于COVID-19相关心肌炎的研究进行概述。

本文引用格式

李玥霖, 赵伊帆, 郝丽英, 胡慧媛△ . COVID-19相关心肌炎的研究进展[J]. 生理科学进展, 2024 , 55(2) : 179 -184 . DOI: 10.20059/j.cnki.pps.2023.12.1101

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that primarily affects the lungs and causes coronavirus disease 2019 (COVID-19). Recent clinical cases have reported the cardiovascular complications of COVID-19, including myocarditis, arrhythmia, myocardial infarction, and so on. Among them, COVID-19-related myocarditis exhibits diverse symptoms, which can occur at different ages and has a delayed onset. Moreover, COVID-19-related myocarditis is positively correlated with the poor prognosis and mortality of COVID-19 patients. The exploration of its clinical characteristics, potential pathogenesis and treatment may provide new ideas and strategies for the prevention and drug development of COVID-19-related myocarditis in the future. This article provides an overview of both domestic and foreign researches on COVID-19-related myocarditis.
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