创伤性脑外伤 (traumatic brain injury, TBI) 是由外力作用引起的脑功能改变或其他脑部病理学变化,是世界范围内的重大公共卫生问题。目前大量研究证明运动作为非药物治疗方式可有效改善TBI。损伤前后的运动均可通过相关机制有益于TBI患者的康复。本文综述了创伤前/后运动对TBI的影响及其潜在调控机制,以期为深入理解运动改善TBI的研究机制及运动疗法在TBI临床中的应用提供理论依据。

Traumatic brain injury (TBI) is defined as functional alterations or other pathological changes in the brain caused by external forces, which is a significant public health issue worldwide. Currently, a large number of studies have proved that exercise, as a nonpharmacological treatment, can effectively improve TBI. Exercise both before and after injury can benefit TBI recovery through specific mechanisms. This article summarizes the effects of exercise before and after injury on TBI and their potential regulatory mechanisms, aiming to provide an in-depth understanding of the mechanisms through which exercise improves TBI, thereby offering a theoretical basis for the clinical application of exercise in the prevention and treatment of TBI.