综述

心理应激对卵巢功能不良影响的研究进展

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  • (1 山东中医药大学第一临床医学院,济南250014; 2 山东中医药大学附属医院妇科, 济南250014)
△ ljx276@sina.com

收稿日期: 2025-08-16

  修回日期: 2025-08-27

  录用日期: 2025-09-10

  网络出版日期: 2025-12-25

基金资助

国家自然科学基金项目(编号:82104917);山东省自然科学基金项目(编号:ZR2021MH079)资助课题

Research Progress on the Adverse Effects of Psychological Stress on Ovarian Function

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  • (1 The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan 250014, China; 2 Department of Gynecology, Affiliated Hospital of Shandong University of TCM , Jinan 250014, China)
△ ljx276@sina.com

Received date: 2025-08-16

  Revised date: 2025-08-27

  Accepted date: 2025-09-10

  Online published: 2025-12-25

摘要

卵巢是女性重要的生殖器官,卵巢功能的损伤不仅对生育能力造成不良影响,也会降低女性的生活质量。心理应激是个体在应对各类压力和挑战时出现的情绪及心理层面的反应, 多种因素都可以作为应激源。长期的心理应激会破坏机体内环境稳态,甚至诱发疾病。当前已有众多研究表明心理应激可通过神经内分泌网络以及代谢途径,影响卵巢局部生理功能,引起卵巢功能的显著变化,导致女性健康问题产生。本文主要综述心理应激影响卵巢功能的相关研究进展, 为相关临床诊疗与研究提供新思路。

本文引用格式

于蕊源1, 于 潇2, 刘金星2, △ . 心理应激对卵巢功能不良影响的研究进展[J]. 生理科学进展, 2025 , 56(6) : 585 -592 . DOI: 10.20059/j.cnki.pps.2025.10.1219

Abstract

The ovaries are vital female reproductive organs. Impairment of ovarian function not only adversely affects fertility but also reduces women's quality of life. Psychological stress refers to the emotional and psychological responses individuals exhibit when confronted with various pressures and challenges, with multiple factors acting as stressors. Chronic psychological stress can disrupt the body's internal homeostasis and even induce diseases. A growing body of research has demonstrated that psychological stress can affect local ovarian physiological functions through neuroendocrine networks and metabolic pathways, causing significant changes in ovarian function, leading to female health issues. This article primarily reviews the research progress on the effects of psychological stress on ovarian function, aiming to provide new insights for associated clinical diagnosis, treatment, and research.
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