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治疗慢性心力衰竭新型器械的研究进展

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  • (1 武汉科技大学附属武汉市武昌医院心血管内科,武汉 430081; 2武汉科技大学医学部医学院,武汉 430065; 3华中科技大学同济医学院附属协和医院心血管外科,武汉 432300)
△ lingtingheyue@163.com

收稿日期: 2024-12-11

  修回日期: 2025-01-08

  录用日期: 2025-01-15

  网络出版日期: 2025-04-25

基金资助

国家重点研发计划(2023YFC2706203)资助课题;湖北省重点实验室开放基金(2023swbx015)资助课题

Novel Device-Based Interventions for Treating Chronic Heart Failure*

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  • (1Department of Cardiology, Wuhan Wuchang Hospital of Wuhan University of Science and Technology, Wuhan 430081, China; 2Medical College, Wuhan University of Science and Technology, Wuhan 430065, China; 3Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 432300, China)
△ lingtingheyue@163.com

Received date: 2024-12-11

  Revised date: 2025-01-08

  Accepted date: 2025-01-15

  Online published: 2025-04-25

摘要

慢性心力衰竭(chronic heart failure)的药物治疗取得了显著进展,但其相关发病率、死亡率和住院率仍然偏高。随着医学技术的不断发展,基于新型设备的干预已成为慢性心力衰竭的潜在治疗方法。近年来研究表明,心房分流器(interatrial shunt device)、压力反射激活治疗(baroreflex activation therapy)和膈神经刺激(phrenic nerve stimulation)在治疗慢性心力衰竭患者方面显示出了良好的前景。本文归纳总结了这些新型治疗设备的工作原理、临床研究成果,并分析其优缺点、可能的风险及未来的应用前景,旨在为临床治疗提供新的思路和参考。

本文引用格式

张 琪1, 2, 王丽岳1, △, 朱晓刚1, 桂 佳1, 黄县立1, 尚小珂3 . 治疗慢性心力衰竭新型器械的研究进展[J]. 生理科学进展, 2025 , 56(2) : 122 -127 . DOI: 10.20059/j.cnki.pps.2025.01.1300

Abstract

Despite remarkable advances in drug therapy for chronic heart failure (CHF), the related morbidity, mortality and hospitalizations remain substantial. Novel device-based interventions have emerged as potential therapies for CHF. Recently, interatrial shunt device (IASD), baroreflex activation therapy (BAT), and phrenic nerve stimulation (PNS) have shown promise in treating patients with CHF. This article summarizes the working principles and clinical research outcomes of these innovative therapeutic devices, and analyzes their advantages and disadvantages, potential risks, and future application prospects, aiming to provide new insights and references for clinical treatment.
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